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Use proteases specificity #237

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douweschulte opened this issue Jul 3, 2023 · 0 comments
Open

Use proteases specificity #237

douweschulte opened this issue Jul 3, 2023 · 0 comments
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M-needs-investigation Misc: Needs looking into by the assignee

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@douweschulte
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Per read it is known which protease generated the peptide, this can be used in the assignment of hard amino acids. Chymotrypsin is known to have specificity after I/L. But a simple search with a sample dataset using database matching gave the impression that this specificity is not 100%. TO actually implement this a more accurate idea on the specificity is needed, after that these specificaties can be weighed in into the consensus sequence.

@douweschulte douweschulte added the M-needs-investigation Misc: Needs looking into by the assignee label Jul 3, 2023
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